Organic Herb Inc.
Model No.: B009.S80100
Source: Macleaya Cordata
Appearance: Fine Brownish Yellow Powder
Latin Name: Macleaya Cordata (Willd.) R. Br.
Specfication: 60% Sanguinarine
Packaging: Drum, Plastic Container, Vacuum Packed, OEM Services Provide
Productivity: 5 Ton per Month
Place of Origin: China
Supply Ability: 5 Ton per Month
Certificate: HACCP,ISO, Halal, Kosher
Macleaya Cordata Extract Powder is extract from macleaya cordata (syn. Bocconia cordata Willd.), a perennial species of flowering plant in the poppy family Papaveraceae,commonly known as Plume Poppy in horticulture. Current studies determined diverse chemical compounds in extracts prepared from Macleayacordata ,especially rich in alkaloids . Using HPLC with UV detection and/or LC/MS with electrospray ionization the alkaloids sanguinarine, chelerythrine, their dihydro derivatives, protopine and allocryptopine and phenolics, gallic, protocatechuic, p-hydroxybenzoic, m-hydroxybenzoic, gentisic, p-coumaric, caffeic, ferulic and sinapic acids were determined from different part of Macleaya Cordata .
Sanguinarine is a toxic quaternary ammonium salt from the group of benzylisoquinoline alkaloids.It is the main ingredient of Macleaya cordata extract. Preliminary pre-clinical in vitro and in vivo studies have demonstrated that sanguinarine causes apoptosis in human cancer cells, and recommend study of sanguinarine as a potential cancer treatment.Sanguinarine is a toxin that kills animal cells through its action on the Na+-K+- ATPase transmembrane protein.If applied to the skin, sanguinarine kills cells and may destroy tissue. In turn, the bleeding wound may produce a massive scab, called an eschar. For this reason, sanguinarine is termed an escharotic.
Another main constitution in Macleay cacordata extract is Chelerythrine , a benzophenanthridine alkaloid .It is a potent, selective, and cell-permeable protein kinase C inhibitor in vitro. It is also found in the plants Zanthoxylum clavaherculis and Zanthoxylum rhoifolium, exhibiting antibacterial activity against Staphylococcus aureus and other human pathogens.
Macleaya cordata (syn. Bocconia cordata Willd.) is a perennial species of flowering plant in the poppy family Papaveraceae,commonly known as Plume Poppy in horticulture.This large herbaceous plant is used ornamentally for its attractive flower panicles, large scalloped leaves and spreading habit.However ,Macleaya cordata also is a source of a variety of chemical compounds which allow it to possess multiple therapeutic actions including antioxidant ,antimicrobial,anticancer ,anti-tumor and insecticidal activity .It has the function of detumescence, detoxification and pesticide.It can be used in the treatment of furuncle, abscess, malignant boil, ulcer, scald and intractable tinea. The extract product is virose and can not be taken orally.
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Product Categories : Standardized Plant Extracts
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