Organic Herb Inc.
Model No.: P002.S10801
Extract Part:: Root Or Leaf
Appearance: Light Yellow Powder
Source: Panax Ginseng
Latin Name: Panax Ginseng C. A. Mey
Specfication: 20~80% Ginsenosides
Packaging: Drum, Plastic Container, Vacuum Packed, OEM Services Provide
Productivity: 50 Ton per Month
Place of Origin: China
Supply Ability: 50 Ton per Month
Certificate: HACCP,ISO, Halal, Kosher
Panax Ginseng Extract is extract from the root or leaf of Panax Ginseng (Asian Ginseng, Chinese Ginseng ). The main active ingredient of Panax Ginseng Extrac is Ginsenosides. Now OHI can supply USP and EP Standard Panax Ginseng Extract with Low Pesticide Residues.
Panax ginseng C.A. Meyer (ginseng) is a well-known medicinal plant that has been traditionally used in the oriental countries for centuries. Ginsenosides or panaxosides are a class of natural product steroid glycosides and triterpene saponins. Compounds in this family are found almost exclusively in the plant genus Panax (ginseng), which has a long history of use in traditional medicine that has led to the study of pharmacological effects of ginseng compounds.
Ginseng is generally consumed orally as a dietary supplement, and thus its component ginsenosides may be metabolized by gut flora. For example, ginsenosides Rb1 and Rb2 are converted to 20-b-O-glucopyranosyl-20(S)-protopanaxadiol or 20(S)-protopanaxadiol by human gut bacteria. This process is known to vary significantly between individuals. In some cases the metabolites of ginsenosides may be the biologically active compounds.
Ginseng is any one of the 11 species of slow-growing perennial plants with fleshy roots, belonging to the genus Panax of the family Araliaceae. Ginseng is found in North America and in eastern Asia (mostly northeast China, Korea, Bhutan, eastern Siberia), typically in cooler climates. Panax vietnamensis, discovered in Vietnam, is the southernmost ginseng known. This article focuses on the species of the series Panax, which are the species claimed to be adaptogens, principally Panax ginseng and P. quinquefolius. Ginseng is characterized by the presence of ginsenosides and gintonin.
Siberian ginseng (Eleutherococcus senticosus) is in the same family, but not genus, as true ginseng. Like ginseng, it is considered to be an adaptogenic herb. The active compounds in Siberian ginseng are eleutherosides, not ginsenosides. Instead of a fleshy root, Siberian ginseng has a woody root.
Over centuries, ginseng has been considered in China as an important component of Chinese traditional medicine, but there is no scientific confirmation of it having any clinical benefit to human health.
Most known ginsenosides are classified as members of the dammarane family. The structure of these dammarane ginsenosides consists of a 4-ring, steroid-like structure. To each ginsenoside is bound at least 2 or 3 hydroxyl groups at the carbon-3 and -20 positions or the carbon-3, -6, and -20 positions respectively. In protopanaxadiols, sugar groups attach to the 3-position of the carbon skeleton, while in comparison sugar groups attach to the carbon-6 position in protopanaxatriols. Well known protopanaxadiols include Rb1, Rb2, Rg3, Rh2, and Rh3. Well known protopanaxatriols include Rg1, Rg2, and Rh1.
Ginsenosides that are a member of the oleanane family are pentacylic, composed of a five ring carbon skeleton.
Most studies of the biological effects of ginsenosides have been in cell culture or animal models and thus their relevance to human biology is unknown. Effects on the cardiovascular system, the central nervous system, the immune system have been reported, primarily in rodents. Antiproliferative effects have also been described.
Many studies suggest that ginsenosides have antioxidant properties. Ginsenosides have been observed to increase internal antioxidant enzymes and act as a free-radical scavenger. Ginsenosides Rg3 and Rh2 have been observed in cell models as having an inhibitory effect on the cell growth of various cancer cells while studies in animal models have suggested that ginsenosides have neuroprotective properties and could be useful in treating neurodegenerative disease such as Alzheimer's and Parkinson's diseases.
Two broad mechanisms of action have been suggested for ginsenoside activity, based on their similarity to steroid hormones. They are amphiphilic and may interact with and change the properties of cell membranes. Some ginsenosides have also been shown to be partial agonists of steroid hormone receptors. It is not known how these mechanisms yield the reported biological effects of ginsenosides. The molecules as a class have low bioavailability due to both metabolism and poor intestinal absorption.
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