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Tripterygium wilfordii Extract Celastrol 98% HPLC
Tripterygium wilfordii Extract Celastrol 98% HPLC
Tripterygium wilfordii Extract Celastrol 98% HPLC
Tripterygium wilfordii Extract Celastrol 98% HPLC
Tripterygium wilfordii Extract Celastrol 98% HPLC

Tripterygium wilfordii Extract Celastrol 98% HPLC

Payment Type: L/C,T/T,D/P,Western Union
Incoterm: FOB,CIF,FCA
Min. Order: 1 Kilogram
Delivery Time: 7 Days

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Basic Info

    Model No.: T005.S99000

    Source: Thunder God Vine

    Latin Name: Tripterygium Wilfordii

    Active Ingredient: Celastrol

    Appearance: Fine Red Powder

    CAS No.: 34157-83-0

    Specfication: 1:1,10:1,98%

Additional Info

    Packaging: Drum, Plastic Container, Vacuum Packed, OEM Services Provide

    Productivity: 1 Ton per Month

    Brand: OHI

    Transportation: Ocean,Land,Air

    Place of Origin: China

    Supply Ability: 1 Ton per Month

    Certificate: HACCP,ISO, Halal, Kosher

Product Description

Celastrol extracted from Tripterygium Wilfordi plant has been reported on [Cell" as having potential as a leptin sensitizer in treating obesity. Tripterygium wilfordii (of the family Celastraceae) is a vine used in traditional Chinese herbal medicine that is referred to as léi gōng téng (Mandarin) but also well known as Thunder God Vine or Thunder Guke Vine.

Mainly grow in China the plant is known as toxic however its pharmacological effects appear against inflammatory and autoimmune diseases . In traditional Chinese herbal medicine the root pulp have effects (to use diction common to traditional medicine) for 'dispelling wind and eliminating dampness, dredging collaterals and relieving pain, reducing swelling and easing pain' therefore is used in treatment for fever, chills, edema, carbuncles and Rheumatoid Arthritis .Nowadays the investigation of Tripterygium wilfordii has expanded its potential usage to treat a variety of disorders including cancer, chronic hepatitis, chronic nephritis, ankylosing spondylitis, polycystic kidney disease, and obesity, as well as several skin disorders.

Although the vine being associated with adverse effects even at moderate doses (diarrhea, headache, nausea and infertility), there are have been progressive researches to investigate a safer usage of Tripterygium wilfordii.

Basic Information of Tripterygium wilfordii Extract Celastrol

  • Product Name: Tripterygium Wilfordii Extract
  • Latin Name: Radix et Rhizoma Tripterygii
  • Active Ingredient: Celastrol
  • CAS: 34157-83-0
  • Specification: 1:1, 10:1, 98%
  • Used Part: Root
  • Appearance: Fine red powder
  • Test Method: TLC & HPLC


The main bio-actives

Since Zhao C G first reported the extract of tripterine(Celastrol ) there are more than 70 compositions have been isolated from Tripterygium wilfordii .Most of those are alkaloids, diterpenes, triterpenoids, sesquiterpenoids and polyose.And the most well known constituents are Wilforine ,Triptolide and Celastrol.

Celastrol (tripterine) is a pentacyclic triterpenoid mainly isolated from the root extracts of Tripterygium wilfordii (Thunder god vine) and exhibits antioxidant ,anti-inflammatory ,
anticancer ,insecticidal activities as well as obesity-controlling effects in mice.
Triptolide is a diterpenoid epoxide that displays immunosuppressive and anti-inflammatory activity.It also has in vitro and in vivo activities against mouse models of polycystic kidney disease and pancreatic cancer.
Triptolide, a diterpene triepoxide, is a major active component of extracts derived from Tripterygium wilfordii as well. Triptolide has multiple pharmacological activities including anti-inflammatory, immune modulation, antiproliferative, and proapoptotic activity.

Functions:

  1. Obesity-control
  2. Contraception
  3. Inflammation inhibition
  4. Immunosuppression
  5. Antitumor

Product application

Despite all modern advances in medicine, an effective drug treatment of obesity has not been found yet.Discovery of Leptin sensitizer is critical as the most powderful energy metabolism control hormone leptin is constantly facing resistance in obese body .Celastrol in tripterygium wilfordii has been indicated as a leptin sensitizer and a promising agent for the pharmacological treatment of obesity.

Also many researches relating tripterygium wilfordii pharmacology shown its positive effects against tumor ,HIV ,inflammatory and autoimmune disorder. In addition to medical applications, tripterygium wilfordii have potential as a very efficient and environmental-friendly insecticidal avail.

Main clinical applications of tripterygium wilfordii are : rheumatic arthritis(RA),lepra reaction ,lupus erythematosus(SLE),dermatomyositis , mixed connective tissue disease(MCTD),Sjogrensyndrome(SS),erythema multiforme ,various types of vasculitis and psoriasis.


organic herb inc(1)

Looking for ideal Tripterygium Wilfordii Extract Manufacturer & supplier ? We have a wide selection at great prices to help you get creative. All the Celastrol 98 HPLC are quality guaranteed. We are China Origin Factory of Thunder God Vine Celastrol. If you have any question, please feel free to contact us.

Product Categories : Active Pharmaceutical Ingredient (API)

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